CREON is the #1 prescribed PERT by GEs, PCPs, NPs, and PAs

CREON® (pancrelipase) #1 Prescribed PERT with 1,000,000+ patients prescribed.

Based on the FDA-approved label, CREON is the only PERT specifically studied in patients with EPI due to chronic pancreatitis and pancreatectomy, in addition to cystic fibrosis1,3

CREON at a glance

Significant experience, exceptional patient support, and excellent coverage make CREON a proven partner for patients with EPl.4,5

10+

years of experience as the first PERT to receive FDA approval (2009)4

More than 8 out of 10

GEs prescribe CREON more than other PERTs2*

90%

of covered lives have preferred coverage and the lowest branded co-pay or co-insurance with commercial insurance and Medicare Part D5†

   Do not substitute other pancreatic enzyme products for CREON1‡

Support programs designed to help patients with EPI every step of the way

CREON Complete logo

For patients with EPI due to conditions other than cystic fibrosis.

For patients with chronic pancreatitis and pancreatectomy or other conditions that are not cystic fibrosis

Eligible patients with commercial insurance may pay as little as $5§ for a 30- or 90-day CREON prescription.

Learn more about CREON Complete.

CFCareForward logo.

For patients with EPI due to cystic fibrosis.


For patients with cystic fibrosis

Eligible patients with commercial insurance may pay as little as $0II for a 30- or 90-day CREON prescription.

Learn more about CFCareForward.

Interested in attending an educational presentation about CREON and EPI?

Take a closer look at how CREON works to replace pancreatic digestive enzymes in patients with EPI.

Formulary definitions: Preferred means the product is placed on the plan's preferred formulary. Lowest Branded Co-Pay means the product is in the formulary tier status designated by the insurer as the lowest branded co-pay in the therapeutic class.

*Per Jan '23–Dec '23 analysis of 12,715 GEs from Subnational XPO. 82% of surveyed GEs had >50% of their PERT prescriptions filled as CREON.2
As of 02/2024. Preferred coverage varies by channel: national commercial (89%) and Medicare Part D (93%). CREON is on a preferred tier or otherwise has preferred status on the plan’s formulary. CREON is on the formulary tier status designated by the insurer as the lowest branded copay in the therapeutic class.5
When switching from another pancreatic enzyme product to CREON, monitor patients for clinical symptoms of exocrine pancreatic insufficiency and titrate the dosage as needed.1
§Eligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit CREONSavingscard.com or call 844-662-7366 for additional information. To learn more about AbbVie’s privacy practices and your privacy choices, visit https://abbv.ie/corpprivacy
IIEligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit CREONCFCFSavingscard.com or call 855-227-3493 for additional information. To learn more about AbbVie’s privacy practices and your privacy choices, visit https://abbv.ie/corpprivacy

EPI = exocrine pancreatic insufficiency; FDA = Food and Drug Administration; GE = gastroenterologist; NP = nurse practitioner; PA = physician assistant; PCP = primary care physician; PERT = pancreatic enzyme replacement therapy.