Symptoms of Exocrine Pancreatic Insufficiency (EPI)

One, some, or all of these symptoms
could mean EPI2


Abdominal Pain



Weight Loss


Steatorrhea—the most common clinical manifestation of EPI—may not appear until the disease is advanced (ie, pancreatic enzyme output drops below 10%).2

Signs and symptoms of EPI may be confused with other GI conditions2

This chart is for informational purposes only. This list is not a complete list of symptoms and it is not intended to be used to diagnose, treat, or care for any particular patient.

IBS-D=irritable bowel syndrome with diarrhea; SIBO=small intestinal bacterial overgrowth.

*Steatorrhea: >7 g of fecal fat per day while consuming 100 g of dietary fat per day.

How EPI Is Diagnosed
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Understand the impact that EPI can have

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What should a treatment plan for EPI include?

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